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pentobarbital will minimize the extent or impact of pimozide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.pentobarbital will increase effects of ifosfamide by influencing hepatic enzyme CYP2B6 metabolism. Use Warning/Check. Coadministration of ifosfamide with CYP2B6 inducers might maximize metabolism of i